WHY IS X-OVO NEXT GENERATION SEQUENCING IMPORTANT?

  • X-OvO, is important because it has created a next generation IB PCR sequencing test, which evaluates a larger part of the IB virus genome, allowing for more accurate IB virus identification.

    The X-OvO database contains:

    • Common commercial Infectious Bronchitis (IB) vaccines used in the field.
    • Major and minor virus populations from a range of commercial vaccine vials (defined using Next Generation Sequencing (NGS) analyses).
    • IB reference strains.

    X-OvO has performed whole genome sequencing of the different commercial IB vaccine vials by means of NGS, identifying each amino acid mutation present in the different viral sub populations contained in each vaccine vial, giving us accurate IB reference strains. These genome sequences can be considered as genetic fingerprints which allow us to differentiate viruses from one another.

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